The loach catfishes are a family, Amphiliidae, of catfishes (order Siluriformes). They are widespread in tropical Africa, but are most common in streams at high elevations; most species are able to cling to rocks in fast-flowing streams. The 13 genera contain 68 species.

The family Amphiliidae has three subfamilies, Amphiliinae, Leptoglanidinae (previously misspelled Leptoglaninae), and Doumeinae. The monophyly of Amphiliidae has been questioned; one author restricts the family to the members of the subfamily Amphiliinae and transferred the other genera to a family Doumeidae. The Amphiliidae have been previously thought to be a basal taxon in the superfamily Loricarioidea, but some authors place their relationships elsewhere.

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