Anisotes is a genus of Afrotropical plants in the family Acanthaceae. The genus is morphologically similar to Metarungia, from which it differs mainly in the dehiscence of the fruit capsule, and the nature of the placenta. Placentas (with attached retinacula) remain attached to the inner surface of fruit capsules in Anisotes.

They favour sandy ground or tropical to subtropical dry forest. The corolla consists of a two-lipped flower that is orange to red in colour. Four seeds are produced in a woody fruit capsule. Two of the six Madagascar species, A. hygroscopicus and A. venosus, are unique in the genus in having hygroscopic trichomes on their seeds.

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