Annona or Anona (from Taíno annon) is a genus of flowering plants in the pawpaw/sugar apple family, Annonaceae. It is the second largest genus in the family after Guatteria, containing approximately 166 species of mostly Neotropical and Afrotropical trees and shrubs.

The generic name derives from anón, a Hispaniolan Taíno word for the fruit. Paleoethnobotanical studies have dated Annona exploitation and cultivation in the Yautepec River region of Mexico to approximately 1000 BC. Plants of the genus have several common names, including sugar-apple, soursop, anona, cherimoya and guanábana.

Currently, seven Annona species (A. cherimola, A. muricata, A. squamosa, A. reticulata, A. senegalensis, A. scleroderma, A. purpurea) and one hybrid (the atemoya) are cultivated for domestic or commercial use, mostly for the edible and nutritious fruits; several others such as A. crassiflora and A. salzmannii also produce edible fruits. Many of the species are used in traditional medicines for the treatment of a variety of diseases, though their efficacy has yet to be validated scientifically. Several annonaceous species have been found to contain acetogenins, a class of natural compounds with a wide variety of biological activities. The first complete genome for a species in this genus (Annona muricata) was published in 2021. The earliest fossils have been found in the Lance Formation dating to the Late Cretaceous.

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