Asclepias curtissii, or Curtiss's milkweed, is a rare species of flowering milkweed that is endemic to Florida's sandy areas. Curtiss's milkweed belongs to the subfamily Asclepiadoideae and the genus Asclepias. This dicotyledonous, perennial plant was placed on the endangered species list by the state of Florida to protect this rare milkweed. Although Curtiss milkweed is found all over Florida, the populations are very isolated and concentrated.

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