Balduina uniflora, commonly called oneflower honeycombhead, savannah honeycombhead or oneflower balduina, is a North American species of plants in the sunflower family. It is native to the southeastern United States (Louisiana, Florida, Georgia, Alabama, Mississippi, South Carolina, North Carolina). It is the type species of the genus Balduina.

Balduina uniflora is a perennial herb with branching stems. Each plant has 1-4 flower heads, each with 8-22 yellow ray florets and 50-180 orange or yellow disc florets. The species grows in wet pinelands and savannahs, as well as wetland areas and on the edges of bogs and tends to occur in wet drainage ditches and on roadsides.

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