Neoboletus subvelutipes, commonly known as the red-mouth bolete, is a bolete fungus in the family Boletaceae. The fruit bodies (mushrooms) have a brown to reddish-brown cap, bright yellow cap flesh, and a stem covered by furfuraceous to punctate ornamentation and dark red hairs at the base. The mushroom rapidly stains blue when sliced or bruised.

It is found in Asia and North America, where it fruits on the ground in a mycorrhizal association with both deciduous and coniferous trees. The fruit bodies are poisonous, causing gastroenteritis-like symptoms if consumed.