The Calpinae are a subfamily of moths in the family Erebidae described by Jean Baptiste Boisduval in 1840. This subfamily includes many species of moths that have a pointed and barbed proboscis adapted to piercing the skins of fruit to feed on juice, and in the case of the several Calyptra species of vampire moths, to piercing the skins of mammals to feed on blood. The subfamily contains some large moths with wingspans longer than 5 cm (2 in).

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