Caymanabyssiidae is a family of sea snails, marine gastropod molluscs in the vaude Vetigastropoda (according to the taxonomy of the Gastropoda by Bouchet & Rocroi, 2005).

This family has no subfamilies. This family was originally the subfamily Caymanabyssiinae Marshall 1985, in the family Pseudococculinidae, containing the genera Caymanabyssia and Colotrachelus. The three other genena were added later by Haszprunar (1988)

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