Cheilomenes sexmaculata is a species of ladybird. Although sometimes known by the common name of six-spotted zigzag ladybird, this is misleading as there are several colour morphs and some colour morphs of the species can be confused with Micraspis discolor and Chilocorus nigrita. The species has a wide distribution range within the Asian tropics and subtropical zones from India to Japan and parts of the Australian region. They have been introduced into the Caribbean islands as a biocontrol agent and their spread to South America was noted in 2019. It is well known as a predator of aphids and other small insects.

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