Colochirus robustus, commonly known as the robust sea cucumber or the yellow sea cucumber, is a species of sea cucumber in the family Cucumariidae. It is found in shallow seas in tropical parts of the central Indo-Pacific region. C. robustus belongs to the class Holothuroidea, a group of echinoderms called sea cucumbers and known for unusual behavior including evisceration, asexual reproduction, and regeneration. The robust sea cucumber has a soft body and lacks a spine, but it does have an endoskeleton consisting of microscopic spicules, or ossicles, made of calcium carbonate. C. robustus has a respiratory tree that allows it to extract oxygen for respiration, using the anus to pump water. The robust sea cucumber is an important dietary staple for many East and Southeast Asian populations, and has been used for medicinal purposes for hundreds of years. Recent research suggests that peptides from C. robustus enhance the activity of the immune system.

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