Cophixalus zweifeli is a species of frog in the family Microhylidae. It is endemic to northern Queensland, Australia, and only known from the area of its type locality in the Cape Melville National Park. The species was named to honour American herpetologist Richard G. Zweifel. Common name Zweifel's frog has been coined for it. It is one of the five northeast Australian Cophixalus species that are specialized in boulder field habitats.

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