Desmonema is a genus of jellyfish under the Cyaneidae family found in colder waters near the Antarctic region and off of the coast of Argentina. They have a bell diameter that can extend over 1 meter and wide tentacles that are grouped together in clusters. They share similar anatomical and physiological structures to the genus Cyanea. Their sophisticated structures like the thick tentacles, sensory systems, and gastrovascular system allow Desmonema to easily capture and extracellularly digest their prey. In recent years, Desmonema were reported to have a commensal relationship with fishes under the Trachurus genus and a parasitic relationship with specimens of the Hyperia genus. The genus name derives from the Ancient Greek desmós (δεσμός), meaning "bond", and nêma (νῆμᾰ), meaning "thread".

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