The Entelegynae or entelegynes are a subgroup of araneomorph spiders, the largest of the two main groups into which the araneomorphs were traditionally divided. Females have a genital plate (epigynum) and a "flow through" fertilization system; males have complex palpal bulbs. Molecular phylogenetic studies have supported the monophyly of Entelegynae (whereas the other traditional subgroup, the Haplogynae, has been shown not to be monophyletic).

The clade contains both cribellate and ecribellate spiders.

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