Ephippion guttifer, commonly known as the prickly puffer, is a species of pufferfish native to the coasts of the eastern Atlantic Ocean from Gibraltar to Angola. This species grows to a length of 80 centimetres (31 in) TL. It is of importance to commercial fisheries and is popular as a gamefish. This species has the ability to get prickly when it puffs up. It is the only known member of the monotypic genus Ephippion.

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