Eupatorium hyssopifolium, also known as hyssopleaf thoroughwort, is a fall-blooming herbaceous plant native to North America. Like other members of the genus Eupatorium it has inflorescences containing a large number of very small flower heads, each with 5 white disc florets but no ray florets. At 0.5 to one meter (20-40 inches) tall, it is towards the shorter end of the range of heights found in Eupatorium species.

Plants which are classified as E. hyssopifolium can be either diploid or polyploid, and some of them seem to have been the result of past hybridizations with Eupatorium serotinum. Hybrids with E. album and E. linearifolium also seem to exist. The hybrid E. torreyanum is similar to E. hyssopifolium but is a hybrid of E. serotinum and Eupatorium mohrii.

Varieties

• Eupatorium hyssopifolium var. hyssopifolium - leaves 2–5 mm wide
• Eupatorium hyssopifolium var. laciniatum A.Gray - leaves 5–15 mm wide

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