Euphorbia griffithii, the Griffith's spurge, is a species of flowering plant in the spurge family Euphorbiaceae, native to Bhutan, Tibet and south west China. It is a spreading, rhizomatous herbaceous perennial growing to 90 cm (35 in), with many erect reddish stems and narrow dark green leaves with red central veins, turning red and yellow in autumn. In summer it produces flowerheads (cyathia) of brilliant red and yellow.

It is a vigorous plant, and can be invasive. Numerous cultivars have been selected for garden use, including 'Dixter' and ‘Fireglow”.

The Latin specific epithet griffithii refers to William Griffith (1810-1845), a British naturalist and botanist.

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