Mussidae is a family of stony coral in the order Scleractinia. Following a taxonomic revision in 2012, the family is now restricted to species found in the Atlantic Ocean, with Pacific species transferred to the new family Lobophylliidae. Many species are referred to as brain coral because their generally spheroid form and grooved surface resembles the convolutions of a brain.

Members of this family are found in the reef aquarium trade. Though popular in captivity, they are under threat from environmental destruction like coral bleaching. The Mussidae is one of the coral families most vulnerable to climate change.

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