Macleania insignis, family Ericaceae is a member of the blueberry family—its most common ancestors in North America include blueberries and cranberries. The family Ericaceae is spread across the world, with a large concentration found in South America. This plant falls within the Neotropical subgroup and then Andean clade of this family. The Psammisia II section shares the closest common ancestor to this plant, and its closest split on a family tree is shared with Macleania coccoloboides and Macleania bullata. Phylogenic classification of M. insignis has primarily been carried out through an examination of morphological traits as well as genetic analysis. Macleania is an angiosperm eudicot, in the order of Ericales and the family Ericaceae.

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