Meganomiinae is a subfamily of melittid bees, with 10 species in four genera, found only in Africa, primarily in xeric habitats, with the distributional limits in Yemen and Madagascar. They are rather different in appearance from the other groups of past/present melittids, being large bees (10–22 mm), mostly black with strong yellow markings, resembling anthidiine megachilids. Males of this subfamily are known to have hidden sterna.

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