Menispermaceae (botanical Latin: 'moonseed family' from Greek mene 'crescent moon' and sperma 'seed') is a family of flowering plants. The alkaloid tubocurarine, a neuromuscular blocker and the active ingredient in the 'tube curare' form of the dart poison curare, is derived from the South American liana Chondrodendron tomentosum, which belongs to this family. Several other South American genera belonging to the family have been used to prepare the 'pot' and 'calabash' forms of curare. The family contains 81 genera with some 440 species, which are distributed throughout low-lying tropical areas with some species present in temperate and arid regions.

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