Microdochium panattonianum is a fungal plant pathogen. This pathogen causes anthracnose of lettuce, a disease which produces necrotic lesions in cultivated lettuce. In extended periods of wet weather, M. panattonianum can cause significant crop-losses. The impact of this pathogen is exacerbated by farming lettuce without crop rotation, and by planting of susceptible lettuce varieties, such as Romaine lettuce.

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