Nabalus barbatus, the barbed rattlesnakeroot, is a plant in the family Asteraceae. It is native to the Southeastern United States where it is found in small numbers in a few disjunct areas of remaining natural grassland. Because of this, it is considered a globally rare species, with only 35-70 remaining populations. Much of its natural habitat of prairie and savanna has been destroyed. In 2010 it was reclassified from the genus Prenanthes to Nabalus.

It is a perennial that flowers in early fall, although flowering has been reported into November.

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