Oreophryne minuta is a species of frog in the family Microhylidae. It is endemic to Papua, Western New Guinea, and only known from its type locality in the Derewo River basin, in the mountains to the southeast of Cenderawasih Bay. It is a very small frog (maximum size 11.5 mm (0.5 in)), and at the time of species description, the smallest Oreophryne species.

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