Oryzomys gorgasi, also known as Gorgas's oryzomys or Gorgas's rice rat, is a rodent in the genus Oryzomys of family Cricetidae. First recorded in 1967, it is known from only a few localities, including a freshwater swamp in the lowlands of northwestern Colombia and a mangrove islet in northwestern Venezuela. It reportedly formerly occurred on the island of Curaçao off northwestern Venezuela; this extinct population has been described as a separate species, O. curasoae, but does not differ morphologically from mainland populations.

O. gorgasi is a medium-sized, brownish species with large, semiaquatically specialized feet. It differs from other Oryzomys species in several features of its skull. Its diet includes crustaceans, insects, and plant material. The species is listed as "Endangered" by the International Union for Conservation of Nature as a result of destruction of its habitat and competition with the introduced black rat (Rattus rattus).

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