Palicourea is a genus of flowering plants in the family Rubiaceae. It contains 694 species, which range from shrubs to small trees, and is distributed throughout the New World tropics.

These plants are closely related to Psychotria and in particular its subgenus Heteropsychotria. Indeed, it seems to be nothing else but a distinctively-flowered offshoot of Heteropsychotria; arguably, it would thus need to be merged into Psychotria to make that genus monophyletic. On the other hand, Psychotria is extremely diverse already, so it is probably more practical to move the more distantly related species out of this genus and merge Heteropsychotria with Palicourea. By a Hungarian botanist Attila Borhidi, some of the Psychotria species have been transferred into this genus.

The genus is not well studied. Most species are distylous, although a few on isolated Caribbean islands seem to have lost the trait. Flowers are in racemes, having no scent, and are normally pollinated by hummingbirds. Blue-black berries follow, and are thought to be distributed by birds.

Almost one-tenth of the Palicourea species are considered threatened by the IUCN, even though the conservation status has only been reviewed for those species that occur in Ecuador.

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