Phoradendron californicum, the desert mistletoe or mesquite mistletoe, is a hemiparasitic plant native to southern California, Nevada, Arizona, Sonora, Sinaloa and Baja California. It can be found in the Mojave and Sonoran Deserts at elevations of up to 1400 m (4600 feet).

The mistletoe is a leafless plant that attaches to host plants, often leguminous woody desert trees such as Cercidium and Prosopis. Desert mistletoe takes water and minerals from its host plants but it does its own photosynthesis, making it a hemiparasite. Desert mistletoes, like mistletoes in general, weave nutrient cycles together through their unique life history.

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