The Ocmulgee slimy salamander (Plethodon ocmulgee) is a species of salamander in the family Plethodontidae. It is endemic to the state of Georgia in the United States, where it is found in regions of the coastal plain and Piedmont that are associated with the Ocmulgee River drainage system. It is only known from a few counties, and due to this restricted range, it is at high risk of extinction. Many populations of this species are already experiencing precipitous declines, with some even possibly being extirpated.

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