The Pseudoxyrhophiidae is a family of elapoid snakes, found mostly in Madagascar. They were formerly placed as a subfamily of the Lamprophiidae, but have been more recently identified as a distinct family.

It contains about 22 genera in two subfamilies:

• Amplorhininae Meirte, 1992
  • Amplorhinus A. Smith, 1847
  • Ditypophis Günther, 1881
  • Duberria Fitzinger, 1826
• Pseudoxyrhophiinae Dowling, 1975
  • Alluaudina Mocquard, 1894
  • Brygophis Domergue & Bour, 1989
  • Compsophis Mocquard, 1894
  • Dromicodryas Boulenger, 1893
  • Elapotinus Jan, 1862
  • Heteroliodon Boettger, 1913
  • Ithycyphus Günther, 1873
  • Langaha Bonnaterre, 1790
  • Leioheterodon Boulenger, 1893
  • Liophidium Boulenger, 1896
  • Liopholidophis Mocquard, 1904
  • Lycodryas Günther, 1879
  • Madagascarophis Mertens, 1952
  • Micropisthodon Mocquard, 1894
  • Pararhadinaea Boettger, 1898
  • Parastenophis Domergue, 1995
  • Phisalixella Domergue, 1995
  • Pseudoxyrhopus Günther, 1881
  • Thamnosophis Jan, 1863

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