Pygopristis is a monospecific genus of freshwater ray-finned fishes belonging to the family Serrasalmidae, which includes the pacus, piranhas and related fishes.. The only species in the genus is Pygopristis denticulata, also known as the lobetoothed piranha,. This species is a rare South American characiform fish found in the Orinoco River basin, rivers of the northern and eastern Guiana Shield, and tributaries of the lower Amazon River. Like other piranhas, it is found in freshwater, with specimens of this species typically found in acidic clearwater or blackwater environments. Despite their ferocious reputation, many piranhas have broader diets; this species feeds on the scales of other fish as juveniles, but transitions to a broader diet of aquatic insects, small fish, and fruits as adults.

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