Symphytognathidae is a family of spiders with 90 described species in eight genera. They occur in the tropics of Central and South America and the Australian region (with Oceania). Exceptions include Anapistula benoiti, Anapistula caecula, and Symphytognatha imbulunga, found in Africa, Anapistula ishikawai, found in Japan, and Anapistula jerai, found in Southeast Asia.

The species Patu digua is considered to be one of the smallest spiders in the world with a body size of 0.37 millimetres (0.015 in).

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