Thalictrum ( ) is a genus of 120-200 species of herbaceous perennial flowering plants in the buttercup family, Ranunculaceae, native mostly to temperate regions. Meadow-rue is a common name for plants in this genus.

Thalictrum is a taxonomically difficult genus with poorly understood species boundaries; it is in need of further taxonomic and field research for clarification.

Despite their common name of "meadow-rue", Thalictrum species are not closely related to the true rue (family Rutaceae), but resemble its members in having compound leaves twice or thrice divided.

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