Tubificinae is a subfamily of annelids belonging to the family Naididae.

The following genera are assigned to Tubificinae:

• Baikalodrilus Holmquist, 1978
• Baltidrilus Timm, 2013
• Christerius Holmquist, 1985
• Clitellio Savigny, 1822
• Ilyodrilus Eisen, 1879
• Isochaetides Hrabĕ, 1966
• Limnodrilus Claparède, 1862
• Potamothrix Vejdovský & Mrázek, 1903
• Psammoryctides Erséus & Healy, 2001
• Tasserkidrilus Holmquist, 1985
• Telliclio Timm, 1978
• Tubifex Lamarck, 1816
• Tubificoides Lastočkin, 1937

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