The Wickerhamomycetaceae are a family of yeasts in the order Phaffomycetales that reproduce by budding. Species in the family have a widespread distribution.

Genus Wickerhamomyces used to be placed within Phaffomycetaceae family, until 2008 when it was separated and placed within its own order Wickerhamomycetaceae.

Beneficially, various Wickerhamomyces species have been used in a number of biotechnologically applications, such as in the environment, food, beverage industries, (including wine making, ) biofuel, medicine and agriculture.

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