Agave gypsophila (common names – gypsum century plant, blue wave agave) is a species of plant in the Asparagaceae family and is endemic to the Mexican state of Guerrero. The specific epithet, gypsophila, means gypsum loving.

Agave gypsophila was described by Howard Scott Gentry in 1982. In 2013, J. Antonio Vazquez-Garcıa, et al. proposed a narrower circumscription of Agave gypsophila based on both ecological and morphological characteristics. The Agave gypsophila sens. lat. (in the broad sense) of Howard Scott Gentry was divided into five species: Agave abisaii, A. andreae, A. gypsophila sens. strict. (in the strict sense), A. kristenii and A. pablocarrillioi. All five species are narrow range endemics in south west Mexico.

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