Dudleya crassifolia is a species of drought deciduous, corm-forming succulent plant known by common name as the thick-leaf dudleya. It is an incredibly rare and cryptic plant native to one small locale less than a hectare in area on the Colonet peninsula in Baja California. It is threatened by urban development, including a proposed seaport. It is characterized by white, spreading flowers with leaf bases that are persistent on the stem. Although it did not receive as much media attention as the neighboring Dudleya hendrixii, it has been noted that the plant has several similarities to cryptic succulents like Anacampseros.

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