Hyperolius bolifambae (also known as Bolifamba reed frog or Medje reed frog) is a species of frog in the family Hyperoliidae. It is known from southeastern Nigeria, southern Cameroon, and southwestern Central African Republic, with an isolated record in northeastern Democratic Republic of the Congo (type locality of Hyperolius erythropus, now in synonymy); the latter record may be considered doubtful. It likely has a broader range towards south and east than currently documented, and the AmphibiaWeb includes Gabon and the Republic of the Congo in the distribution.

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