Hyperolius spinigularis is a species of frog in the family Hyperoliidae. It is found in the Mulanje Massif in southern Malawi and the Namuli Massif in adjacent Mozambique. Records from Tanzania refers to other species. Males of this species have characteristic small spines during the breeding season. Its common names are spiny-throated reed frog, spiny reed frog, and Mulanje reed frog.

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