Lycium is a genus of flowering plants in the nightshade family, Solanaceae. The genus has a disjunct distribution around the globe, with species occurring on most continents in temperate and subtropical regions. South America has the most species, followed by North America and southern Africa. There are several scattered across Europe and Asia, and one is native to Australia. Common English names for plants of this genus include box-thorn, wolfberry, and desert-thorn. Plants of the World Online currently accepts 101 species. Other estimates are of 70 to 80 species.

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