Tetrapterys is a genus of flowering plants in the family Malpighiaceae, native to Latin America and the Caribbean, from Mexico through to Argentina, but excluding Chile. Small trees, shrubs or vines, they are known to be toxic to livestock if consumed for long periods of time, and T. mucronata and T. styloptera (formerly T. methystica) have hallucinogenic effects in humans similar to ayahuasca.

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