Vitis labrusca, the fox grape, is a species of grapevines belonging to the Vitis genus in the flowering plant family Vitaceae. The vines are native to eastern North America and are the source of many grape cultivars, including Catawba, Concord, Delaware, Isabella, Niagara, and many hybrid grape varieties such as Agawam, Alexander and Onaka. Among the characteristics of this vine species in contrast to the European wine grape Vitis vinifera are its "slip-skin" that allows the skin of the grape berries to easily slip off when squeezed, instead of crushing the pulp, and the presence of tendrils on every node of the cane. Labruscana also tend to have strong resistance to mildews and phyloxerra. Another contrast with European vinifera are unique flavors, best known to most people through the Concord grape. The term "foxy" became a sort of catchall for the wine tasting descriptors used for these American wines that were distinct from the familiar flavors of the European viniferous wines. These flavors have been described as strawberry, raspberry, cotton candy, and "grapey" (because Americans associate these flavors with popular grape juices, candies, jellies and jams, sodas, and more made with Concord grapes). Occasionally, depending on the winemaking, labrusca grapes can impart a musky flavor to wine, which some find intriguing while others dislike, but this can be mitigated or increased by winegrowing and winemaking practices. Vitis labrusca is in the parentage of the world's most planted grape variety, Kyoho.

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