Synodontis acanthoperca, known as the scissortail synodontis, is a species of upside-down catfish native to Gabon where it occurs in the Ogowe River. It was first described by John Patrick Friel & Thomas R. Vigliotta in 2006, based upon a holotype discovered in the Ogooué River in Gabon, at and below the Rapids of Massoukou. The specific name "acanthoperca" comes from the Latinized combination of the Greek word acantha, meaning "thorn", and the Latin opercul, meaning cover or lid, which refers to the pronounced spines that develop on the operculum of mature males.

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