Synodontis pardalis is a species of upside-down catfish that is endemic to Cameroon where it occurs in the Dja River drainage. It was first described by British-Belgian zoologist George Albert Boulenger in 1908, from specimens collected in the Dja River in southern Cameroon. The species name pardalis is derived from the Greek word pardalis, which means "leopard", which refers to the spotted pattern on the fish.

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