Synodontis iturii is a species of upside-down catfish that is endemic to the Democratic Republic of the Congo where it is only known from the Ituri River. It was first described by Franz Steindachner in 1911. The original specimens were obtained in the Ituri River, in what is now the Democratic Republic of the Congo. The species name iturii is derived from the Ituri River, where the species was discovered.

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