Synodontis sorex is a species of upside-down catfish that is widely distributed in the rivers of northern Africa. It was first described by German zoologist Albert Günther in 1864, from specimens obtained in the upper Nile River, near Khartoum, Sudan. The species name sorex comes from the Latin word for shrew or shrew-mouse, the allusion was not explained. It possibly describes the pointed snout or the long, slender teeth.

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